The use of next-generation sequencing (NGS) has revolutionised the diagnosis and management of viral infections. Currently, clinical virology laboratories can perform whole genome sequencing and screening of hundreds of virus-infected samples within hours, enabling real-time genomics for diagnostics, transmission investigation, and infection control.

The course combines hands-on laboratory work with expert-led lectures focusing on cutting-edge NGS viral genome sequencing and analysis techniques. Participants will learn to prepare sequencing libraries using advanced methods like target enrichment and long-read technologies. The course offers practical training in bioinformatics, including the Linux/UNIX command line. It covers key aspects such as data quality control, reference mapping, de novo assembly of viral genomes, and phylogenetic analysis. Real-world case studies will highlight NGS's practical applications and challenges in clinical settings.